• Re: Great scholarly article on sleep definitions, self repair etc - pin

    From Jeremy H. Denisovan@1:229/2 to thang ornerythinchus on Monday, August 21, 2017 14:35:43
    From: david.j.worrell@gmail.com

    On Friday, August 18, 2017 at 6:27:18 PM UTC-7, thang ornerythinchus wrote:
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008810/

    Snippets: ->

    Sleep can be defined as a reversible behavioural state in which an
    individual is perceptually disengaged from and unresponsive to the environment.

    Sleep is a complex physiological and behavioural state that has two
    primary states based on physiological parameters. These are rapid eye movement (REM) and non-rapid eye movement (NREM) sleep. An electroencephalogram in which electrodes measure brain electrical
    activity is used to identify the two states (Fig. 1).

    NREM sleep is divided into four stages, which are associated with a progressive increase in the depth of sleep [12].

    FYI. In 2007, stages 3 and 4 were combined into a single 'stage 3'
    representing deep sleep. So Stage 3 is now the deep sleep stage.
    And thus, they say now there are three NREM stages.

    Dreaming can occur in the NREM stages of sleep. Also, in REM.
    Dreaming in the NREM stages tends to be "more mundane", whereas
    dreaming in the REM stage tends to be "more vivid and bizarre".


    REM sleep is characterized by muscle atonia, bursts of REM and
    dreaming. Therefore, REM sleep is considered to be a condition with an activated brain in a paralysed body.

    According to a 2005 Gallup Poll in the US, the average self-reported
    sleep duration of healthy individuals is 6.8 h on weekdays and 7.4 h
    on weekends

    (that's about my patterns - maybe a bit longer on weekends, a bit
    shorter during the week).

    That's pretty close to what I usually do too.


    Naps can markedly reduce sleepiness and can be beneficial when
    learning skills, strategy or tactics [32]. Napping may also be
    beneficial for athletes who have to wake early routinely for training
    or competition and those who are experiencing sleep deprivation [32].

    I like taking a midday nap, and yet often I don't.


    One of the most studied areas of sleep deprivation research relates to effects on alertness and performance [34]. In this instance
    ‘performance’ is generally defined as goal-directed behaviour
    requiring mental effort. Performance deficits due to sleep deprivation
    are well acknowledged and understood, and it is estimated that the consequences cost billions of dollars worldwide per year due to
    accidents, direct healthcare costs, and reduced efficiency and
    productivity [34]. Learning and memory deficits are also evident after
    sleep deprivation. It appears that sleep is important not only
    following learning for consolidation of memory, but also for preparing
    the brain for next-day memory formation [35].

    there is also recent evidence suggesting that sleep deprivation may
    cause or modulate acute and chronic pain [36]. Sleep deprivation may
    thus enhance or cause pain, and pain may disturb sleep by inducing
    arousals during sleep. A cycle may then eventuate, starting with
    either pain or sleep deprivation, with these two issues maintaining or augmenting each other [36].

    sleep improves immune responses and that most immune cells have their
    peak pro-inflammatory activity at night [37]. Disruptions in endocrine
    and physiological circadian rhythms due to sleep deprivation may
    result in impaired immune responses, giving rise to an increased risk
    of illness.

    Both laboratory and epidemiological studies support the notion that
    chronic partial sleep loss can increase the risk of obesity and
    diabetes [42]. Potential mechanisms include changes in glucose
    regulation by insulin resistance, dysregulation of neuroendocrine
    control of appetite and/or increased energy intake [42, 43]

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